AN EVALUATION OF THE DRUG PERMEABILITY PROPERTIES OF HUMAN CADAVERIC IN SITU TYMPANIC AND ROUND WINDOW MEMBRANES

An Evaluation of the Drug Permeability Properties of Human Cadaveric In Situ Tympanic and Round Window Membranes

It is estimated that hearing loss currently affects more than 1.5 billion people, or approximately 20% of the global population; however, presently, there are no Food and Drug Administration-approved therapeutics or prophylactics for this condition.While continued research on the development of otoprotective drugs to target this clear unmet need is

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Homoharringtonine demonstrates a cytotoxic effect against triple-negative breast cancer cell lines and acts synergistically with paclitaxel

Abstract The lack of targeted therapies for triple-negative breast cancer (TNBC) contributes to their high mortality rates and high risk of relapse compared to other subtypes of breast cancer.Most TNBCs (75%) have downregulated the expression of CREB3L1 (cAMP-responsive element binding protein 3 like Crisps 1), a transcription factor and metastasis

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Transformations Of Contemporary Arab Criticism: From The Paradigm Of Simplification To The Paradigm Of Complexity And Pluralism: The Reception Of Interdisciplinary Sciences In Contemporary Arab Criticism

Abstract: In the second half of the twentieth century, the world witnessed a scientific revolution that impacted various fields, including literary criticism.This period saw an increase in cultural openness to the West, which influenced Arab criticism, leading it to adopt Western theories and approaches in Champagne Bucket studying literary texts.T

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The acute effects of strength, endurance and concurrent exercises on the Akt/mTOR/p70S6K1 and AMPK signaling pathway responses in rat skeletal muscle

The activation of competing Ball - Floorball intracellular pathways has been proposed to explain the reduced training adaptations after concurrent strength and endurance exercises (CE).The present study investigated the acute effects of CE, strength exercises (SE), and endurance exercises (EE) on phosphorylated/total ratios of selected AMPK and Akt

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